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江湖救急,实在不知道该怎么回答审稿人的问题了啊!求大神帮忙!
小弟最近收到了杂志的意见,1号审稿人同意发表。2号审稿人体的问题着实不知道该怎么回答,还请各位虫友帮帮忙啊!!!!!江湖救急!
意见如下:
In figure 5 and 6 authors showed that there is increase in mRNA and protein expression of I&kappa&B&alpha& after Con-A injection which is reversed by 某治疗药物. But as a matter of fact I&kappa&B&alpha& gets ubiquitinated and phosphorylated by IKK&beta& and subsequently degraded before the activation of NF-&kappa&B to induce cytokine production. But, here this is not the fact and on the contrary, in this study after 某治疗药物 treatment, there is a reduction in I&kappa&B&alpha& and also NF-&kappa&B expression which is going against the hypothesis of the manuscript and the classical pathway. I would suggest the authors to clarify the issue.
到底该怎么回复呢。。。。。。:cry::cry::cry::cry:
我知道啊 但是我在想怎么回答,因为IKB和NFKB同时身高,我觉得可能是我选择的作用时间点的原因。
这个专业问题学过生物的我半斤八两,请教一下周围比较专业的吧
或者在生物科学或分子生物版块问问
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随时随地聊科研500字,描写学校花园,求神人.
游园朝代:宋 作者:叶茵 碧琅?裹几亭台,万朵芙蕖照水开.可醉可吟尤可卧,主人无暇客长来.
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